//Ceftriaxone Sodium

Ceftriaxone Sodium

CAS number: 74578-69-1

Molecular formula: C18H16N8Na2O7S3

molecular weight: 598.5436

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Product Description

Description Ceftriaxone sodium salt is an antibiotic useful for the treatment of a number of bacterial infections.Target: AntibacterialCeftriaxone inhibits bacterial cell wall synthesis by means of binding to the penicillin-binding proteins (PBPs). Inhibition of PBPs would in turn inhibit the transpeptidation step in peptidoglycan synthesis which is required for bacterial cell walls. Like other cephalosporins, ceftriaxone is bacteriocidal and exhibits time-dependent killing. Ceftriaxone, one of the beta-lactam antibiotics, is a stimulator of EAAT2 expression with neuroprotective effects in both in vitro and in vivo models based in part on its ability to inhibit neuronal cell death by glutamate excitotoxicity. Based on this consideration and its lack of toxicity, ceftriaxone has potential to manipulate glutamate transmission and ameliorate neurotoxicity.
Solvent
In Vitro:

H2O : ≥ 40 mg/mL (66.83 mM)

“≥” means soluble, but saturation unknown.

Solubility
1 mM 1.6707 mL 8.3537 mL 16.7073 mL
5 mM 0.3341 mL 1.6707 mL 3.3415 mL
10 mM 0.1671 mL 0.8354 mL 1.6707 mL
Storage 4°C, protect from light

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