//Chloramphenicol

Chloramphenicol

CAS number: 56-75-7

Molecular formula: C11H12Cl2N2O5

molecular weight: 323.1294

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Product Description

Description Chloramphenicol is a broad-spectrum antibiotic.Target: AntibacterialChloramphenicol is a bacteriostatic drug that stops bacterial growth by inhibiting protein synthesis. Chloramphenicol prevents protein chain elongation by inhibiting the peptidyl transferase activity of the bacterial ribosome. It specifically binds to A2451 and A2452 residues in the 23S rRNA of the 50S ribosomal subunit, preventing peptide bond formation. While chloramphenicol and the macrolide class of antibiotics both interact with ribosomes, chloramphenicol is not a macrolide. It directly interferes with substrate binding, whereas macrolides sterically block the progression of the growing peptide
Density 1.6±0.1 g/cm3
Boiling Point 563.2±60.0 °C at 760 mmHg
Melting Point 148-150 °C(lit.)
Molecular Formula C11H12Cl2N2O5
Molecular Weight 323.129
Flash Point 294.4±32.9 °C
Exact Mass 322.012329
PSA 115.38000
LogP 1.62
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.623
Water Solubility 2.5 g/L (25 º C)

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