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CAS Number | 19387-91-8 |
---|---|
Molecular Formula | C8H13N3O4S |
Molecular Weight | 247.271 |
Boiling point | 528.4±30.0 °C at 760 mmHg |
Melting Point | 117-121 °C(lit.) |
Color | White powder |
CAS Number | 19387-91-8 |
---|---|
Molecular Formula | C8H13N3O4S |
Molecular Weight | 247.271 |
Boiling point | 528.4±30.0 °C at 760 mmHg |
Melting Point | 117-121 °C(lit.) |
Color | White powder |
Tinidazole is an antiprotozoal, antibacterial agent. The nitro- group of tinidazole is reduced by cell extracts of Trichomonas. The free nitro- radical generated as a result of this reduction may be responsible for the antiprotozoal activity. Chemically reduced tinidazole was shown to release nitrites and cause damage to purified bacterial DNA in vitro. Additionally, the drug caused DNA base changes in bacterial cells and DNA strand breakage in mammalian cells. The mechanism by which tinidazole exhibits activity against Giardia and Entamoeba species is not known.
Synonym: Tinidazole; Bioshik; CP 12,574; CP 12574; CP-12,574; CP-12574; CP12,574; CP12574; Farmasierra; Fasigin; Fasigyn; Fasigyne; Fasygin; Simplotan; Teofarma; Tinidazole; Tricolam
IUPAC/Chemical Name: 1-(2-ethylsulfonylethyl)-2-methyl-5-nitroimidazole
InChi Key: HJLSLZFTEKNLFI-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
SMILES Code: O=[N+](C1=CN=C(C)N1CCS(=O)(CC)=O)[O-]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
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